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Association details:
Biomarker:
EGFR expression
Cancer:
Glioblastoma
Drug:
Koselugo (selumetinib)
(
MEK inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Cancer Commun (Lond)
Title:
Proteomics identifies EGF-like domain multiple 7 as a potential therapeutic target for epidermal growth factor receptor-positive glioma
Published date:
09/04/2020
Excerpt:
Selumetinib treatment showed tumor reduction effect in EGFR-positive glioblastoma xenograft mouse model.
DOI:
10.1002/cac2.12092
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