^
Association details:
| Biomarker: | EGFR exon 20 insertion |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | Vizimpro (dacomitinib) (pan-HER inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry
Excerpt:
A 54-year-old African-American male...received treatment with Erlotinib for a total of two cycles...DNA sequencing analysis revealed that the patient's tumor sample harbored an EGFR mutation in exon 20 (N771GY)...the exon 20 insertion mutations were sensitive to PF00299804.
DOI:
https://doi.org/10.1038/onc.2010.545
