^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

The bispecific antibody MCLA-129 impairs NSCLC tumor growth by targeting EGFR and c-MET, inhibiting ligand-induced signaling and promoting ADCC and ADCP

Published date:
03/10/2021
Excerpt:
Significant tumor regression was observed following treatment of immunodeficient xenograft NSG-hHGFki mice bearing orthotopic tumors established from HCC827EGFR del (E746, A750) cells.