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Association details:
Biomarker:EGFR E709K
Cancer:Non Small Cell Lung Cancer
Drug:erlotinib (EGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
New
Source:
Title:

Early Radiographic Response to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor in Non-small Cell Lung Cancer Patients with Epidermal Growth Factor Receptor Mutations: A Prospective Study

Excerpt:
Table 2: Clinical features of 39 adenocarcinoma patients of lung treated with EGFR‑TKI....In conclusion, this prospective study demonstrated a high correlation (72.4%) in the radiological response between early (Day 14) and regular evaluation time (Day 56), and a very high percentage (21/29, 72.4%) of early radiological response to EGFR‑TKIs in NSCLC patients with EGFR mutations and PR, which would advocate early radiological examination for EGFR‑TKI therapy in NSCLC patients.
DOI:
10.4103/2319-4170.138320