^
Association details:
Biomarker:EGFR C797S
Cancer:Lung Cancer
Drug Class:EGFR inhibitor
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Title:

BRAF fusion in lung cancer

Published date:
05/29/2020
Excerpt:
...Nine patients received EGFR-TKI therapy...the median TTD (time to discontinue) of TKIs was 26 months (range 17 to 46). The EGFR mutation still exist when EGFR-TKIs resistance, included EGFR primary mutation, T790M, and C797S, concurrent with BRAF fusion.
DOI:
10.1200/JCO.2020.38.15_suppl.e21598