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Association details:
| Biomarker: | EGFR C797S + EGFR T790M + EGFR exon 19 deletion |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | TAS3351 (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
3259 / 1 - TAS3351 is a 4th-generation EGFR-TKI overcoming T790M and C797S-mediated resistance in NSCLC with EGFR common mutations
Published date:
03/09/2022
Excerpt:
TAS3351 demonstrated favorable anti-tumor activity in NIH/3T3 allografts transformed by human EGFR harboring ex19del/C797S/T790M.
