^
Association details:
Biomarker:DFNB31 V400A
Cancer:Colorectal Cancer
Drug:Erbitux (cetuximab) (EGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Title:

Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Excerpt:
Among these 9 chemosensitive SNPs, specific genotypes of 3 SNPs (ANXA11 rs1049550, LINS1 rs11247226, and DFNB31 rs2274159) were associated with objective or disease control responses...
DOI:
10.1158/1078-0432.CCR-10-1907