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Association details:
| Biomarker: | DDR |
|---|---|
| Cancer: | Melanoma |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
1640 - Correlations of DNA damage response gene alterations with response to immune checkpoint inhibitors are different in solid tumors
Published date:
03/10/2021
Excerpt:
DDR alterations are associated with ICIs efficacy in melanoma (P = 0.0007), colorectal cancer (P = 0.0012), NSCLC (P = 0.0224), bladder cancer (P = 0.0439), and breast cancer (P = 0.0451).
