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Association details:
| Biomarker: | CYP4B1 expression |
|---|---|
| Cancer: | Lung Cancer |
| Drug Class: | Immunotherapy |
| Direction: | Resistant |
Evidence:
Source:
Title:
1716P - Prognostic value and immune characteristics of CYP4B1 in lung squamous cell carcinoma: A bioinformatics analysis
Published date:
09/05/2022
Excerpt:
Unlike LUAD, CYP4B1 expression is associated with worse OS in LUSC. This might be due to the infiltration of Tregs and M2 cells even though there were also higher CD8+ cells and lower MDSC. Thus, CYP4B1 might serve as an important predictive and prognostic biomarker in patients treated with immunotherapy.
