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Association details:
| Biomarker: | CXCR3 overexpression |
|---|---|
| Cancer: | Urothelial Cancer |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Activation of the chemokine receptor 3 pathway leads to a better response to immune checkpoint inhibitors in patients with metastatic urothelial carcinoma
Published date:
05/13/2022
Excerpt:
In the ICI cohort, we performed univariate and multivariate COX analyses and discovered that patients in the CXCR3-high group were more sensitive to ICI treatment.
DOI:
10.1186/s12935-022-02604-z