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Association details:
Biomarker:CXCL12 elevation
Cancer:Hepatocellular Cancer
Drug Class:T-lymphocyte cell therapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

Efficacy and biomarker analysis of CD133-directed CAR T cells in advanced hepatocellular carcinoma: a single-arm, open-label, phase II trial

Published date:
11/25/2020
Excerpt:
This phase II study investigated CD133-directed chimeric antigen receptor (CAR) T (CART-133) cells in adults with HCC….higher plasma levels of sVEGFR2 and SDF-1 were significantly correlated with a longer OS…
DOI:
10.1080/2162402X.2020.1846926
Trial ID: