^
Association details:
| Biomarker: | CUL4A overexpression |
|---|---|
| Cancer: | Multiple Myeloma |
| Drug: | lenalidomide (TNFα inhibitor, IL-6 inhibitor, IL-12 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
EXPRESSION SIGNIFICANCE OF CRL4-CRBN PROTEINS COMPLEX IN MULTIPLE MYELOMA PATIENTS TREATED WITH IMMUNOMODULATORY DRUGS.
Published date:
05/14/2020
Excerpt:
...the high CUL4A expression was associated with better response to IMiDs treatment (p=0.013) and longer PFS in comparison to the group of patient with low CUL4A level (p=0.027).
