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Association details:
| Biomarker: | CTSS overexpression |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | temozolomide (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Title:
[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]
Excerpt:
To investigate the expression of cathepsin S (CTSS) in temozolomide-resistant glioblastoma T98G (T98G-R) cells…Both mRNA and protein levels of CTSS in T98G-R cells were significantly higher than those in T98G cells.
