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    Association details:
    Biomarker:CTSG expression
    Cancer:Soft Tissue Sarcoma
    Drug Class:Immunotherapy
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    Source:
    Front Oncol
    Title:

    The Potential of Five Immune-Related Prognostic Genes to Predict Survival and Response to Immune Checkpoint Inhibitors for Soft Tissue Sarcomas Based on Multi-Omic Study

    Published date:
    07/24/2020
    Excerpt:
    Gene expression data from the Cancer Genome Atlas were used to identify the immune-related prognostic genes (IRPGs)...The IGRPM was constructed using five IRPGs (IFIH1, CTSG, STC2, SECTM1, and BIRC5)….Five IRPGs performed well in risk stratification of patients and are candidate biomarkers for predicting response to immunotherapy.
    DOI:
    10.3389/fonc.2020.01317