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    Association details:
    Biomarker:CSMD1 overexpression
    Cancer:Breast Cancer
    Drug:anastrozole (Aromatase inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    JCI Insight
    Title:

    Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action

    Published date:
    07/23/2020
    Excerpt:
    Overexpression of CSMD1 sensitized AI-resistant cells to anastrozole but not to the other two AIs.
    DOI:
    10.1172/jci.insight.137571