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    Association details:
    Biomarker:CRLF2 mutation
    Cancer:Acute Lymphocytic Leukemia
    Drug:cyclophosphamide (Alkylating agent)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Int J Lab Hematol.
    Title:

    Effects of different aberrations in the CRLF2 gene on the biological characteristics and drug sensitivities of Nalm6 cells

    Published date:
    12/04/2020
    Excerpt:
    Cells with aberrations in CRLF2 were more resistant to cyclophosphamide and drugs commonly used during treatment than cells in the vector group.
    DOI:
    10.1111/ijlh.13419