^
Association details:
| Biomarker: | COL1A1-PDGFB fusion |
|---|---|
| Cancer: | Sarcoma |
| Drug: | pazopanib (Multi-tyrosine kinase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Extensive analysis of 59 sarcoma-related fusion genes identified pazopanib as a potential inhibitor to COL1A1-PDGFB fusion gene
Published date:
08/17/2023
Excerpt:
The sensitivity to 12 drugs including multityrosine kinase inhibitors was assessed using the MANO method and pazopanib was found to be more effective against cells expressing the COL1A1-PDGFB fusion gene compared with the others.
DOI:
https://doi.org/10.1111/cas.15915
