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Association details:
| Biomarker: | CMTM6 overexpression + PD-L1 overexpression |
|---|---|
| Cancer: | Melanoma |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy
Published date:
12/29/2020
Excerpt:
...we characterize CMTM6 expression in melanoma and evaluate its association with response to immune checkpoint inhibitors (ICI)...high CMTM6 and PD-L1 co-expression in the stromal compartment was significantly associated with longer survival in treated patients (P = .028). Consequently, CMTM6 expression shows potential as a predictive factor for ICI treatments.
DOI:
10.1080/2162402X.2020.1864909
