^
Association details:
| Biomarker: | CLDN6 positive |
|---|---|
| Cancer: | Soft Tissue Sarcoma |
| Drug Class: | T-lymphocyte cell therapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
BNT211: A phase I/IIa trial to evaluate safety and efficacy of CLDN6 CAR-T and CARVac-based in vivo expansion to improve treatment of patients with CLDN6-positive advanced solid tumors
Published date:
05/07/2021
Excerpt:
Patients with CLDN6-positive relapsed or refractory solid tumors...The underlying diseases of the first three patients were ovarian carcinoma, desmoplastic round small cell tumor and yolk sac carcinoma….In case of patient 2, stable disease with evidence of tumor shrinkage (-19.7%, target lesions) is observed.
