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Association details:
Biomarker:Chr t(3;5)(q25;q35)
Cancer:Acute Myelogenous Leukemia
Regimen:7+3 (DAC) (cladribine + cytarabine + daunorubicin)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

Identification of a cryptic submicroscopic deletion using a combination of fluorescence in situ hybridization and array comparative genomic hybridization in a t(3;5)(q25;q35)-positive acute myeloid leukemia patient: A case report and review of the literature

Published date:
10/23/2020
Excerpt:
We present a 47-year-old man with acute myeloid leukemia. G-banding analysis identified t(3;5)(q25;q35)....The patient started "7+3" induction chemotherapy with cytosine arabinoside and daunorubicin, and subsequently received 2 cycles of high-dose intermittent acronym of cytosine arabinoside or cytarabine....The patient did not undergo complete remission and died from an infection due to neutropenia.
DOI:
10.1097/MD.0000000000022789