^
Association details:
Biomarker:Chr t(14;20)
Cancer:Multiple Myeloma
Drug Class:Proteasome inhibitor +
Immunomodulator
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

Cytogenetic abnormalities in MM: Association with disease characteristics and treatment response.

Published date:
05/29/2020
Excerpt:
The rate of ≥ very good partial response was higher for patients with high risk IgH translocations [t(4;14), t(14;16) or t(14;20)] compared to standard risk with PI-IMiD combination treatment (88% vs 65% P < 0.01).
DOI:
10.1200/JCO.2020.38.15_suppl.e20520