CLL/SLL with del(17p)/TP53 mutation: First-line therapy...Preferred regimens…Acalabrutinib ± obinutuzumab
Evidence Level:
Sensitive: C1 - Off-label
(Approved for Chronic Lymphocytic Leukemia)
New
Excerpt:
acalabrutinib (Calquence) is accepted for restricted use within NHSScotland....as monotherapy for the treatment of adult patients with previously untreated CLL who have a 17p deletion or TP53 mutation and in whom chemoimmunotherapy is unsuitable.