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    Association details:
    Biomarker:CFTR expression
    Cancer:Lung Adenocarcinoma
    Drug Class:CFTR potentiator
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    J Cancer Res Clin Oncol
    Title:

    CFTR reduces the proliferation of lung adenocarcinoma and is a strong predictor of survival in both smokers and non-smokers

    Published date:
    06/17/2022
    Excerpt:
    Further in vitro experiments using naturally CFTR expressing lung adenocarcinoma cells showed that treatment with CFTR potentiators significantly reduced proliferation at therapeutically relevant concentrations.
    DOI:
    https://doi.org/10.1007/s00432-022-04106-x