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Association details:
| Biomarker: | CEACAM6 overexpression |
|---|---|
| Cancer: | Gastric Cancer |
| Drug: | 5-fluorouracil (Thymidylate synthase inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Dual role of carcinoembryonic antigen-related cell adhesion molecule 6 expression in predicting the overall survival of gastric cancer patients
Published date:
09/07/2017
Excerpt:
These findings suggest that patients with high CEACAM6 or CEA expression are not sensitive to 5-FU treatment. CEACAM6 overexpression increased apoptotic resistance in MKN45 and SGC7901 GC cell lines compared to controls.
DOI:
10.1038/s41598-017-11482-9
