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Association details:
Biomarker:CDX-2 expression
Cancer:Breast Cancer
Drug:tamoxifen (Estrogen receptor antagonist)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

CDX2-positive breast cancer presented with axillary lymph node metastases: A case report

Published date:
12/29/2020
Excerpt:
We report a rare case of CDX2-positive metastatic breast cancer in the axillary LNs….The final pathological diagnosis was T1bN3aM0 stage IIIC. The fluorescent double staining showed that CDX2 simultaneously expressed on the Ki67 positive cells of metastatic tumors. The adjuvant treatment included chemotherapy and radiation, followed by tamoxifen administration. The patient survived without any recurrences over the following 36 months.
Secondary therapy:
Chemotherapy
DOI:
10.1016/j.ctarc.2020.100300