^
Association details:
| Biomarker: | CDK4 overexpression |
|---|---|
| Cancer: | Ependymoma |
| Drug: | Verzenio (abemaciclib) (CDK4 inhibitor, CDK6 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Abemaciclib, A Selective CDK4/6 Inhibitor, Restricts the Growth of Pediatric Ependymomas
Excerpt:
...CDK4 and CCND1 are overexpressed in ependymomas...Abemaciclib treatment inhibits patient-derived ependymoma xenografts growth in vivo…
DOI:
10.3390/cancers12123597
