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Association details:
Biomarker:
CD8 expression
Cancer:
Renal Cell Carcinoma
Drug:
Opdivo (nivolumab)
(
PD1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ASCO-GU 2020
Title:
Integrative genomic profiling of RCC treated with second-line nivolumab.
Published date:
02/14/2020
Excerpt:
Integrative genomic sequencing analysis of ccRCC tumors in Nivolumab treated patients revealed CD8 expression as a putative biomarker.
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