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    Association details:
    Biomarker:CD74-ROS1 fusion
    Cancer:Lung Adenocarcinoma
    Drug:pemetrexed (Thymidylate synthase inhibitor, THF dehydrogenase inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C4 – Case Studies
    Source:
    Thorac Cancer
    Title:

    A case of CD74-ROS1-positive lung adenocarcinoma diagnosed by next-generation sequencing achieved long-term survival with pemetrexed regimens

    Published date:
    07/24/2023
    Excerpt:
    ...we report a rare case of CD74-ROS1-positive lung adenocarcinoma diagnosed by NGS that achieved long-term survival with cytotoxic drugs, especially PEM regimens.
    DOI:
    https://doi.org/10.1111/1759-7714.15041