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Association details:
| Biomarker: | CD73 overexpression |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Role of HLA-I as a Molecular Prognostic Factor for Long Term Responders in Non-small Cell Lung Cancer Patients Treated with Immunotherapy
Published date:
08/08/2023
Excerpt:
We evaluated the immunophenotype in a cohort of 145 metastatic NSCLC patients who received treatment with ICIs based regimens for metastatic setting…LTR patients had higher HLA-I expression ( 68%) than non-LTR (35%) (p= 0.013). Median CD73 expression was higher in LTR: 35% ( 95% CI 10-57.5) than non-LTR: 5% ( 95% CI 0-23.8) p=0.007.
