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    Association details:
    Biomarker:CD40 expression
    Cancer:Leukemia
    Drug:bortezomib (Proteasome inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    Source:
    ESMO.org
    Title:

    GENE EXPRESSION PROFILING OF PROSPECTIVE SERIES IN PRIMARY PLASMA CELL LEUKEMIA REVEALED GENE SIGNATURE ASSOCIATED WITH SURVIVAL

    Published date:
    05/17/2018
    Excerpt:
    Patients received induction therapy composed of bortezomib, doxorubicin, cyclophosphamide and dexamethasone....2 genes: WNT5B and CD40, reached a highly significant correlation (BY. P value < 0,05) with OS…
    Secondary therapy:
    cyclophosphamide