^
    Back
    Association details:
    Biomarker:CD34 positive
    Cancer:Chronic Myeloid Leukemia
    Drug:imatinib (Bcr-abl inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Cell Mol Life Sci
    Title:

    miR-181a plays the tumor-suppressor role in chronic myeloid leukemia CD34 + cells partially via SERPINE1

    Published date:
    12/16/2023
    Excerpt:
    Herein, we showed that miR-181a inhibited the growth of CML CD34+ cells, including the quiescent subset, and sensitized them to IM treatment…
    DOI:
    10.1007/s00018-023-05036-8