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Association details:
| Biomarker: | CD19 positive + Chr t(8;21) |
|---|---|
| Cancer: | Acute Myelogenous Leukemia |
| Drug Class: | T-lymphocyte cell therapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Successful treatment of two relapsed/refractory t(8;21) acute myeloid leukemia patients by CD19-directed chimeric antigen receptor T cells
Excerpt:
...CAR-T-19 is a promising and safe approach to managing R/R CD19 positive t(8;21)AML. Application of CAR-T-19 may provide a salvage and potentially curative treatment approach and benefit a certain population of CD19 positive AML besides B-linage malignancies.
