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Association details:
| Biomarker: | CD133 rs3130 |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Avastin (bevacizumab) (VEGF-A inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Association of CD133 polymorphisms and response to bevacizumab in patients with metastatic colorectal cancer
Excerpt:
The rs3130 CC genotype was associated with reduced toxicity of treatments (p= 0.0017), and with lower overall survival on bevacizumab (p= 0.002).
DOI:
10.3233/CBM-150528
