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Association details:
Biomarker:CD133 expression
Cancer:Glioblastoma
Drug:dacarbazine (DNA synthesis inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Title:

Flow cytometry analysis of neural differentiation markers expression in human glioblastomas may predict their response to chemotherapy

Excerpt:
The expression of A2B5, CD56, NGFR and Pgp appeared to be associated with chemoresistance whereas CD133, EGFR and LIFR expression was characteristic of chemosensitive tumours...
DOI:
10.1007/s10571-009-9366-6