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Association details:
Biomarker:
CCND1 overexpression
Cancer:
Estrogen Receptor Positive Breast Cancer
Drug:
tamoxifen
(
Estrogen receptor antagonist
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Br J Cancer
Title:
Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients
Published date:
05/17/2004
Excerpt:
Our results suggest that cyclin D1 overexpression predicts for tamoxifen treatment resistance in breast cancer…
DOI:
10.1038/sj.bjc.6601831
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