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Association details:
| Biomarker: | CCAT2 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | 5-fluorouracil (Thymidylate synthase inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Long noncoding RNA CCAT2 reduces chemosensitivity to 5-fluorouracil in breast cancer cells by activating the mTOR axis
Published date:
02/15/2022
Excerpt:
Compared with parent BC cells, CCAT2 expression in 5-Fu drug-resistant cells was evidently increased (all p < 0.05) (Figure 1C), suggesting that CCAT2 may influence the drug sensitivity of BC cells to 5-Fu.
DOI:
10.1111/jcmm.17041
