^
Association details:
Biomarker:CARS1‐ALK fusion
Cancer:Sarcoma
Drug:Alecensa (alectinib) (ALK inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Source:
Title:

Metastatic Low-Grade Sarcoma with CARS-ALK Fusion Dramatically Responded to Multiple ALK Tyrosine Kinase Inhibitors: A Case Report with Comprehensive Genomic Analysis

Published date:
09/30/2020
Excerpt:
...a case of advanced metastatic low‐grade sarcoma...The patient was detected to have CARS‐ALK fusion by NGS...the patient has been responding well to the second‐line ALK tyrosine kinase inhibitor alectinib to date.
DOI:
10.1002/ONCO.13543