^
Association details:
Biomarker:BRAF V600R
Cancer:Melanoma
Drug:Mekinist (trametinib) (MEK inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Title:

Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor

Excerpt:
One patient each with BRAF K601E and BRAF V600R had prolonged PR.
DOI:
10.1200/JCO.2012.43.5966
Trial ID: