^
Association details:
| Biomarker: | BRAF V600E |
|---|---|
| Cancer: | Thyroid Gland Medullary Carcinoma |
| Drug: | CI-1040 (MEK inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Inhibitory Effects of the Mitogen-Activated Protein Kinase Kinase Inhibitor CI-1040 on the Proliferation and Tumor Growth of Thyroid Cancer Cells with BRAF or RAS Mutations
Excerpt:
Genotypes of various thyroid cancer cell lines and their sensitivity to inhibition by CI-1040.
DOI:
https://doi.org/10.1210/jc.2007-0097
