^
Association details:
| Biomarker: | BRAF V600E |
|---|---|
| Cancer: | Thyroid Gland Carcinoma |
| Drug: | AZ 628 (pan-RAF inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
An integrated model of RAF inhibitor action predicts inhibitor activity against oncogenic BRAF signaling
Excerpt:
Furthermore, in BRAFV600E colorectal and thyroid cancer cells lines in which VEM was ineffective, all treatments including TAK and LY led to potent suppression of cell growth within 10 days of treatment (Figure 7E).
DOI:
10.1016/j.ccell.2016.06.024
