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Association details:
Biomarker:BRAF V600E
Cancer:Colorectal Cancer
Drug Class:MAPK inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

Clinical and pathologic factors associated with survival in BRAFV600E colorectal cancers.

Published date:
05/13/2020
Excerpt:
Durable responses to MAPK-targeted therapies (5/25) and immunotherapy (3/25) were noted in the favorable group….Pts with BRAFV600E mCRC can achieve excellent long-term survival which belies conventional context and is driven by locoregional and systemic treatment options alike.
DOI:
10.1200/JCO.2020.38.15_suppl.4047