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Association details:
| Biomarker: | BRAF V600E + TERT mutation |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | Zelboraf (vemurafenib) (BRAF inhibitor, BRAF V600E inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Effective treatment of a BRAF V600E-mutant epithelioid glioblastoma patient by vemurafenib: a case report
Published date:
07/04/2021
Excerpt:
...long-term surviving 37-years-old men patient diagnosed with a BRAF V600E and TERT mutated E-GBM with wild-type in the isocitrate dehydrogenase gene (IDH wild-type)...After postoperative conventional treatment options were exhausted, vemurafenib treatment was initiated. The patient remained clinically stable...
DOI:
10.1097/CAD.0000000000001130
