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Association details:
| Biomarker: | BRAF V600 |
|---|---|
| Cancer: | Colon Cancer |
| Drug: | ABM-1310 (BRAF V600E inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
ABM-1310, A novel BRAF Inhibitor, combined with EGFR and MEK inhibitors, inhibits colorectal tumor growth and increases overall survival in vivo
Published date:
05/15/2020
Excerpt:
...ABM-1310, as a novel small molecule BRAF inhibitor, combined with EGFR and MEK inhibitors, has shown strong anti-tumor effect in preclinical in vivo models of colon cancer with BRAFv600 mutation, especially with brain metastasis.
