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Association details:
Biomarker:
BRAF G596V
Cancer:
Lung Adenocarcinoma
Drug:
Zelboraf (vemurafenib)
(
BRAF inhibitor
,
BRAF V600E inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
New
Source:
J Thorac Oncol
Title:
Targeted Therapy for Patients with BRAF-Mutant Lung Cancer Results from the European EURAF Cohort
Excerpt:
From the 6 patients with non-V600E, one (17%) with G596V had PR with vemurafenib….One patient with G596V achieved PR with vemurafenib.
DOI:
10.1097/JTO.0000000000000625
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