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Association details:
Biomarker:
BRAF G469R
Cancer:
Non Small Cell Lung Cancer
Drug:
sorafenib
(
Multi-tyrosine kinase inhibitor
,
pan-RAF inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
New
Source:
Anticancer Drugs
Title:
A significant response to sorafenib in a woman with advanced lung adenocarcinoma and a BRAF non-V600 mutation
Excerpt:
...a case report of a patient with NSCLC and the BRAF G469R mutation who showed a dramatic response to sorafenib.
DOI:
10.1097/CAD.0000000000000277
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