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Association details:
| Biomarker: | BIRC3‐MALT1 fusion |
|---|---|
| Cancer: | Lymphoma |
| Drug: | MI-2 (Menin-MLL inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Establishment and characterization of a MALT lymphoma cell line carrying an API2-MALT1 translocation
Published date:
04/29/2020
Excerpt:
...a novel lymphoma cell line named BMA19, carrying the API2‐MALT1 translocation from a patient...The MALT1 inhibitor MI‐2 specifically decreased cell growth, and the BMA19 cell line was suggested to be still dependent on the API2‐MALT1 signal.
DOI:
10.1002/gcc.22855
