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Association details:
| Biomarker: | BICD1 overexpression |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | temozolomide (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
BICD1 expression, as a potential biomarker for prognosis and predicting response to therapy in patients with glioblastomas
Excerpt:
First, high BICD1 expression was correlated with poor prognosis in the TCGA GBM cohort (n=523) and in the CGGA glioma cohort (n=220). high BICD1 expression may result in worse prognosis and could be a predictor of poor response to TMZ and radiation therapies in GBM patients.
DOI:
10.18632/oncotarget.22667
