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Association details:
Biomarker:BCL7A mutation
Cancer:Follicular Lymphoma
Regimen:R-CHOP (cyclophosphamide + doxorubicin hydrochloride + + Rituxan (rituximab) + vincristine)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Title:

MUTATIONAL PROFILE IN NEWLY DIAGNOSED FOLLICULAR LYMPHOMA AND CORRELATION WITH OUTCOME AFTER TREATMENT WITH INMUNOCHEMOTHERAPY

Published date:
06/12/2020
Excerpt:
Among genes frequently mutated, we observed an association with worse PFS in cases bearing mutations in KMT2D, BCL7A and ARID1B…Despite being infrequent, PLCG2 and TNFA1P3 mutated cases showed a statistically significant dismal outcome…