^
Association details:
Biomarker:ATM deletion
Cancer:Bladder Cancer
Drug Class:PARP inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

ATM deficiency confers specific therapeutic vulnerabilities in bladder cancer

Published date:
11/22/2023
Excerpt:
...we observed a significant increase in PARP inhibitor sensitivity in all ATM-deleted cell lines compared to WT ATM parental lines...
DOI:
10.1126/sciadv.adg2263