^
Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

150 Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia

Published date:
11/03/2022
Excerpt:
Finally, we demonstrated the in vivo efficacy of CHZ868 in PAX5::JAK2, ATF7IP::JAK2 and ZEB2::JAK2 patient-derived- xenografts.
DOI:
https://doi.org/10.1182/blood-2022-169437